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Your Guide to Dimethylformamide: Specs, Uses & Supply

Explore the properties, applications, and benefits of DMF.

What is Dimethylformamide (DMF)?

Dimethylformamide (DMF) is a highly polar organic solvent recognized for its versatility across a wide range of industrial and chemical applications. Known for its ability to dissolve a variety of organic and inorganic compounds, DMF plays a key role in everything from polymer production to pharmaceutical synthesis. With a high boiling point and strong solvency power, DMF is a go-to material for manufacturers seeking consistent performance and reliability. 

Product Specs

Chemical Formula: C₃H₇NO

CAS #: 68-12-2

Trade Names: DMF, N,N-Dimethylformamide

Appearance: Colorless liquid

Acidity: pKa ~0.36 (very weak acid)

Molecular Weight: 73.09 g/mol

pH: Neutral to slightly basic in aqueous solution

Key Uses of Dimethylformamide

DMF is valued for its exceptional solvency, high boiling point, and chemical stability—qualities that make it indispensable in a wide range of industrial processes. Below are three key industries where DMF plays a critical role. 

Chemical Manufacturing

In chemical manufacturing, DMF acts as a universal solvent and reaction medium in complex processes. Because of its ability to dissolve a wide variety of compounds, DMF often improves yield, purity, and reaction efficiency. It’s commonly used in:

  • Specialty chemical processes, particularly where high-polarity solvents are needed to support difficult or sensitive reactions
  • Production of pharmaceuticals and agrochemicals as a carrier solvent during formulation and synthesis
  • Polymer and resin manufacturing, including polyacrylonitrile and polyurethane

Metalworking

DMF is used in metal surface treatment processes and electrolytic plating baths where strong solvency is required. Its stability and miscibility make it ideal for use in demanding environments where precision and consistency are critical, such as: 

  • Intermediate in catalyst preparation, helping improve coating adhesion and metal finish consistency
  • Solvent for degreasing formulations for precision parts cleaning
  • Carrier for electrolytic solutions in plating operations, especially when a stable, non-aqueous medium is necessary

Paints and Coatings

DMF serves as a high-performance solvent in the formulation of industrial-grade coatings and finishes. Its functions include:

  • Acting as a co-solvent in applications that require uniform film formation on complex surfaces.
  • Solubilizing resins and polymers in specialty coating systems
  • Improving flow, leveling, and drying characteristics in polyurethane, epoxy, and alkyd-based coatings

Its slow evaporation rate and compatibility with a wide range of binders make DMF a preferred choice in coatings for automotive, aerospace, and industrial equipment.

Dimethylformamide Supplier: Meadows Chemical

When it comes to sourcing DMF, consistency, flexibility, and cost-efficiency are non-negotiable. That’s where Meadows Chemical delivers—especially for companies looking beyond just prime products. 

With decades of experience in chemical distribution and a business model built around speed, service, and solutions, Meadows Chemical specializes in matching customers with the right DMF for their needs, including high-quality secondary and off-spec material that’s ideal for less spec-sensitive applications.

Whether you’re optimizing your budget or looking to reduce sourcing risk, we can help you take advantage of material others overlook without sacrificing performance or delivery.

Meadows Chemical provides:

  • Consistent secondary and byproduct DMF supply, plus access to prime when needed
  • Fast, reliable logistics, built around urgency and real-world production timelines
  • Flexible pricing and procurement terms, backed by strong credit and sourcing networks
  • Expert guidance to help you align technical needs with real-world cost targets

In a market where volatility and lead time issues are the norm, our ability to move high-value secondary product gives our customers a smart, strategic edge—delivering supply others can’t, at prices others won’t.

Request More Information Here

Dimethylformamide FAQs

Is Dimethylformamide toxic?

Yes, DMF can be toxic if inhaled, ingested, or absorbed through the skin in large amounts. It’s classified as harmful and should be handled with proper safety protocols, including PPE and adequate ventilation.

Is Dimethylformamide soluble in water?

Yes, DMF is completely miscible with water. Its polar nature allows it to mix easily with water and many other organic solvents.

What is Dimethylformamide used for?

DMF is primarily used as a solvent in the production of fibers, pharmaceuticals, and industrial coatings. It also serves as a chemical intermediate and reaction medium in many synthetic processes.

Get in Touch With Meadows Chemical

If you need Dimethylformamide in bulk, or you’re open to exploring alternative supply paths that don’t compromise your process, Meadows Chemical is your solution partner.

Contact us today today to learn more about Dimethylformamide, download the sds, or request a price quote.

Explore the properties, applications, and benefits of DMF.

What is Dimethylformamide (DMF)?

Dimethylformamide (DMF) is a highly polar organic solvent recognized for its versatility across a wide range of industrial and chemical applications. Known for its ability to dissolve a variety of organic and inorganic compounds, DMF plays a key role in everything from polymer production to pharmaceutical synthesis. With a high boiling point and strong solvency power, DMF is a go-to material for manufacturers seeking consistent performance and reliability. 

Product Specs

Chemical Formula: C₃H₇NO

CAS #: 68-12-2

Trade Names: DMF, N,N-Dimethylformamide

Appearance: Colorless liquid

Acidity: pKa ~0.36 (very weak acid)

Molecular Weight: 73.09 g/mol

pH: Neutral to slightly basic in aqueous solution

Key Uses of Dimethylformamide

DMF is valued for its exceptional solvency, high boiling point, and chemical stability—qualities that make it indispensable in a wide range of industrial processes. Below are three key industries where DMF plays a critical role. 

Chemical Manufacturing

In chemical manufacturing, DMF acts as a universal solvent and reaction medium in complex processes. Because of its ability to dissolve a wide variety of compounds, DMF often improves yield, purity, and reaction efficiency. It’s commonly used in:

  • Specialty chemical processes, particularly where high-polarity solvents are needed to support difficult or sensitive reactions
  • Production of pharmaceuticals and agrochemicals as a carrier solvent during formulation and synthesis
  • Polymer and resin manufacturing, including polyacrylonitrile and polyurethane

Metalworking

DMF is used in metal surface treatment processes and electrolytic plating baths where strong solvency is required. Its stability and miscibility make it ideal for use in demanding environments where precision and consistency are critical, such as: 

  • Intermediate in catalyst preparation, helping improve coating adhesion and metal finish consistency
  • Solvent for degreasing formulations for precision parts cleaning
  • Carrier for electrolytic solutions in plating operations, especially when a stable, non-aqueous medium is necessary

Paints and Coatings

DMF serves as a high-performance solvent in the formulation of industrial-grade coatings and finishes. Its functions include:

  • Acting as a co-solvent in applications that require uniform film formation on complex surfaces.
  • Solubilizing resins and polymers in specialty coating systems
  • Improving flow, leveling, and drying characteristics in polyurethane, epoxy, and alkyd-based coatings

Its slow evaporation rate and compatibility with a wide range of binders make DMF a preferred choice in coatings for automotive, aerospace, and industrial equipment.

Dimethylformamide Supplier: Meadows Chemical

When it comes to sourcing DMF, consistency, flexibility, and cost-efficiency are non-negotiable. That’s where Meadows Chemical delivers—especially for companies looking beyond just prime products. 

With decades of experience in chemical distribution and a business model built around speed, service, and solutions, Meadows Chemical specializes in matching customers with the right DMF for their needs, including high-quality secondary and off-spec material that’s ideal for less spec-sensitive applications.

Whether you’re optimizing your budget or looking to reduce sourcing risk, we can help you take advantage of material others overlook without sacrificing performance or delivery.

Meadows Chemical provides:

  • Consistent secondary and byproduct DMF supply, plus access to prime when needed
  • Fast, reliable logistics, built around urgency and real-world production timelines
  • Flexible pricing and procurement terms, backed by strong credit and sourcing networks
  • Expert guidance to help you align technical needs with real-world cost targets

In a market where volatility and lead time issues are the norm, our ability to move high-value secondary product gives our customers a smart, strategic edge—delivering supply others can’t, at prices others won’t.

Request More Information Here

Dimethylformamide FAQs

Is Dimethylformamide toxic?

Yes, DMF can be toxic if inhaled, ingested, or absorbed through the skin in large amounts. It’s classified as harmful and should be handled with proper safety protocols, including PPE and adequate ventilation.

Is Dimethylformamide soluble in water?

Yes, DMF is completely miscible with water. Its polar nature allows it to mix easily with water and many other organic solvents.

What is Dimethylformamide used for?

DMF is primarily used as a solvent in the production of fibers, pharmaceuticals, and industrial coatings. It also serves as a chemical intermediate and reaction medium in many synthetic processes.

Get in Touch With Meadows Chemical

If you need Dimethylformamide in bulk, or you’re open to exploring alternative supply paths that don’t compromise your process, Meadows Chemical is your solution partner.

Contact us today today to learn more about Dimethylformamide, download the sds, or request a price quote.

July 2, 2025 by

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Meadows Chemical is a Houston-based company with 25+ years of experience distributing industrial chemicals, solvents, and petroleum-based products. We proudly represent 30+ trusted manufacturers and serve customers across the globe.


9575 Katy Freeway, Ste 100
Houston, Texas 77024
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